It is found in deep water off the Atlantic coastline of Europe and Northern Africa. It is the only remaining extant species in the genus Glossus.

Glossus humanus has a shell reaching up to 160 mm in length, but usually it is between 60 and 80 mm. This shell is globular with a subcircular outline. The two valves viewed from the side are heart shaped, forming the outline of a human heart (hence the original species name, Cardium humanum).

The walls of the shell are quite thin, equivalve, with a light weight. The outer surface usually is dark brown or olive green, with fine radial lines and frequently covered with short hairs.

Glossus humanus lives half buried into the substratum, exposing only the lower margin of the shell and the siphon. It feeds on plankton and other microscopic particles that it filters out with its gills. Spawning occurs at the end of September. This species occurs in soft muddy or sandy substrates, from depths of 7 m up to 250 m, but more frequently below 50 m.

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